HMS Cairo (D87) was a C-class light cruiser of the Royal Navy, named after the Egyptian city of Cairo. She was laid down by Cammell Laird at Birkenhead on 28 November 1917, launched on 19 November 1918 and commissioned on 24 September 1919. She was converted to an anti-aircraft cruiser in 1939.
In World War II she took part in the Norwegian campaign where she was damaged by German planes off Narvik.
In August 1942, Cairo (Capt. C.C. Hardy, DSO, RN) took part in Operation Pedestal, the escorting of a convoy to Malta. During the operation she was sunk by one torpedo from the Italian submarine Axum, north of Bizerta, Tunisia on 12 August 1942.